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We have a lot of concerns with drugs in Columbia South Carolina. We could possibly get through most situations so long as we can preserve the lives of the ones we love. Using two separate drugs to shed pounds can be very effective you'll find combinations while watching FDA now awaiting approval. When dealing with weight loss and the people who go through it you should err on the side of caution and permit the FDA do its job and demand some investigation be done so that the public is aware of the side effects and dangers of the medications before we bring them. Keep in mind that drug companies are in business to make money and that they would say almost anything to keep people on the medications. Researchers found that participants using this drug to get a year, lost weight within 4 weeks and have kept the load off through the 56 weeks from the study. Contrave is really a combination from the drugs naltrexone and bupropion, which appears to reflect a whole new trend of weight-loss drugs which can be made up of many active ingredient, that might make them more effective and safer. Combo-pilling could be the newest fad or also the newest into the future under scrutiny and therefore it is just more publicly known although in the past, comb-pilling for losing weight has been around since the eighties. The biggest reason that by using a combination of pills is becoming popular will be the fact that at the time of right now there are no long term prescription slimming capsules that have been authorized by the FDA apart from orlistat. The truly disturbing part is the fact that doctors are prescribing these combinations of medications although some people might of the combinations are already rejected or have yet to be authorized by the FDA. Seizures really are a side effect with Contrave and really should not be taken in people who have seizure disorders. The drug also can raise blood pressure and heartbeat, and mustn't be used in those with a history of cardiac event or stroke in the earlier six months. Blood pressure and pulse should also be measured prior to starting the drug and throughout therapy while using drug. The FDA also warned that Contrave can raise hypertension and heart rate and must not be used in patients with uncontrolled high blood pressure, as well as by anyone with heart-related and cerebrovascular (blood vessel dysfunction impacting the mind) disease. Patients using a history of cardiac arrest or stroke in the earlier six months, life-threatening arrhythmias, or congestive heart failure were excluded in the clinical trials. Those taking Contrave needs to have their heart-rate and pulse monitored regularly. In addition, because the compound includes bupropion, Contrave comes having a boxed warning to alert medical researchers and patients for the increased probability of suicidal thoughts and behaviors linked to antidepressant drugs. The warning also notes that serious neuropsychiatric events are actually reported in patients taking bupropion for smoking cessation. From a psychiatric viewpoint, evidence shows that the ordinary neural mechanism for goal-directed behavior may be hijacked from the addiction, and malfunctions in such a way that its ordinary functions are exaggerated and fixated on its object. An object creates a stimulus and also the person engages in a "goal-directed behavioral response" that generates a "natural high"(Bostwick & Bucci, 2008).